1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the treatment of numerous myeloma. Its synthesis or study is essential for making sure the purity and safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor within the synthesis of abiraterone acetate, a drug Employed in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound inside the synthesis of imatinib, a drug that targets particular types of most cancers, like Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats different cancers which include breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are typically intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their study is essential for optimizing the generation approach and making sure superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is employed to deal with breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist used in the cure of breast most cancers. Various intermediates help in the synthesis of the drug.
Paclitaxel Facet Chain Abiraterone Acetate Intermediate Acid (CAS NO. 949023-16-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers for instance ovarian, breast, and lung most cancers.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the therapy of colorectal cancer and modest cell lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, which have several programs, like antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for sort two diabetic issues that inhibits the enzyme DPP-four to control blood sugar amounts.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved with the synthesis of assorted gluconic acid derivatives, which are used in food items, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication 17-(3-pyridinyl)- applied to deal with type two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).